Prevalence and Severity of Anemia in CKD patients

Background:Anemia is one of the well-recognized and significant complications of chronic kidney disease (CKD) which manifests noteworthy association with the progression of CKD, the inevitable necessity for blood transfusion, prolonged hospitalization. This study aimed to conduct a comprehensive study as regards the prevalence of anemia and its association with laboratory parameters in CKD patients.
Methods:The Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation was applied to calculate the estimated glomerular filtration rate (eGFR) and the patients with hemoglobin (Hb) level < 13.0 g/dL in case of males and that < 12.0 g/dL in females was defined as anemic. The patients were stratified according to their Hb level into four different categories: Hb 12 g/dL.
Results:Demographic status of CKD patients: Male/Female = 106/123 (M/F% = 46.28/53.71) with mean age 54.94 ± 17.98 and 55.13 ± 14.27, respectively.  Out of 229 CKD patients, 157 (69%) were anemic, and 72 (31%) patients were non-anemic. The mean eGFR of anemic and non-anemic CKD patients was 10.14 ±13.57 and35.74 ± 30.36 with a significance level (P<0.001). Anemia was more prevalent in females’ (36%) than males’ patients (32%).  The Prevalence for Hb < 12 g/dL for male and female patients was 55.29% and 79.25%, respectively, while that < 11 g/dL for male and female was found to be 39.03% and 63.21%.
Conclusion:The prevalence of anemia in CKD population is notable and correlates with the progression of CKD