Study the Hypersensitivity Type 1 in Patients Suffering from Drug and Asthma Allergy

Mahmood, Asmaa E.; Rasheed, Hajar K.

doi:10.21608/eajbsc.2023.322409

Study the Hypersensitivity Type 1 in Patients Suffering from Drug and Asthma Allergy

Document Type : Original Article

Authors

Department of Pathological Analysis, College of Applied Sciences, University of Samarra, Iraq

10.21608/eajbsc.2023.322409

Abstract

The current study was conducted to measure some immunoglobulin IgE, IgG, IgM, some interleukins interleukin 4 (IL-4), interleukin 5 (IL-5) and a complete blood count (CBC) in patients suffering from hypersensitivity type 1 (drug allergy, and asthma). The study began from 1/9/2022 to 1/3/2023 and included 59 people of all ages. The current results showed that people with drug allergy and asthma had an increase in the concentration of IL-4 (407.8 ±27.0), (837.6 ± 29.4), IL-5 (323.1 ±39.7) (568.4 ± 32.1) respectively. The level of IgE, IgG and IgM was elevated in patients suffering from drug allergies (11.2±2.6) (18.1±2.8) (and 47.9±5.3) respectively and asthma was (30.3±3.4), (26.1 ± 4.6) and (50.2 ± 8.6) respectively.
The results of the complete blood count showed a significant increase in the white blood cells, Eosinphile. In addition to many differences in blood parameters compared to normal proportions. It was also found that the IgE concentration decreased with age, while the IgG antibody concentration increased compared to the standard sample and with the increase in age groups.

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