Epidemiological, Clinical, and Pathological Characteristics of Gastric Carcinoma in The Northwest Region of Algeria: A Single Center Study

Document Type : Original Article

Authors

1 Biology Department, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria. -Laboratory of Molecular Microbiology Health and Proteomics, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria. Algeria. -Laboratory of Molecular Microbiology Health and Proteomics, Faculty of Natural Sciences

2 Biology Department, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria.

3 Biology Department, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria. -Laboratory of Molecular Microbiology Health and Proteomics, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria.

4 Departement of medical oncology. Anti-cancer centre of Sidi Bel Abbes. Algeria.

Abstract

Introduction: Cancer of the stomach is a serious public health issue due to its frequency and severity. It is one of the most common causes of cancer-related death for both sexes and is a major contributor to the global burden of disease. To better understand the epidemiological, clinical, and pathological characteristics of gastric cancer in the Western Algerian region Sidi Bel Abbes, our study aimed to investigate the prevalence, risk factors, and clinical outcomes of gastric cancer in this region.Methods: The medical records of 131 patients with gastric cancer in the Sidi Bel Abbes region between January 2015 and December 2019 were reviewed retrospectively in order to gain insight into the epidemiology of gastric cancer in the region.Result: The results of this statistical analysis indicate that there is a male predominance in the cases studied and that the average age of the patients is 61.069 years. Histologically,
carcinoma is the most common histological type (87.7%). 77.1% of cases were diagnosed in stages III and IV of TNM, and 46.6% of cases were found in the pyloric antrum. 38.2% of the cases had atrophic chronic gastritis as a precancerous lesion, and 16.8% had acute or chronic gastritis. Conclusion: The diagnosis of gastric cancer is often made at a late stage with a poor prognosis. However, in order to develop strategies for prevention and early detection, extensive research is still needed to identify the risk factors for gastric cancer.

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