Primary Broncho-Pulmonary Cancer in Women: Epidemiological Study, Clinical-Pathological Study and Therapeutic Load.

Document Type : Original Article

Authors

1 Département de Biologie, Faculté des Sciences de la Nature et de la Vie, Université Djillai LIABES Sidi Bel Abbès

2 Département de Biologie, Institut des Sciences exactes et Sciences de la Nature et de la Vie, Centre universitaire Ahmad ZABANA, Relizane

Abstract

Introduction: Primary bronchial cancer in women is a major public health problem; its incidence has increased steadily over the past 20 years.
Objective: The objective of this work was to analyze the epidemiological, clinical, therapeutic and prognostic characteristics of lung cancer in women in the region of Sidi Bel Abbés.
Materials and methods: A descriptive retrospective study of 50 women diagnosed with primary lung cancer collected in the oncology and radiotherapy department of anti cancer centre between January 2008 and May 2019.
Results: The average age of our patients was 64 years
(±15,063). Respiratory symptoms were dominated by chest pain. The main risk factors were passive smoking (26% of cases), family history of cancer, hormonal factors, environmental factors, history of respiratory diseases.
The most common histological type was adenocarcinoma (74% of cases), stages III and IV accounted for 95% of cases. The main metastatic locations were bone and cervical (23.8%). Treatment management was based mainly on chemotherapy (50% of cases), of which 19% were palliative.
Discussion: Our results confirm that bronchial cancer in women is steadily increasing. Its risk factors are different from those of men. The dominant histological type in women was adenocarcinoma, which has a better prognosis, however, the diagnosis remains late, which explains the predominance of stages III and IV in women.
Conclusion: The female primary broncho-pulmonary cancer has anatomopathological, hormonal and genetic peculiarities that characterize it, which should encourage us to apprehend it differently from the therapeutic strategies better for women

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