Influence of Cardiopulmonary Bypass on Some Antioxidants and Haematological Measurements in Cardiac Patients and Associated Diseases

Document Type : Original Article

Authors

1 Zoology and Entomology Department, Faculty of Science, Al-Azhar University

2 Cardio-Thoracic Surgery Unit, Kasr El-Aini hospital, Faculty of Medicine, Cairo University

Abstract

The current work aims to explore the potential impact of cardiopulmonary bypass risk on blood picture and cardiac functions in patients with an open heart and associated diseases. The study was conducted in five groups, twenty healthy people and eighty patients from cardiac surgery and related diseases such as diabetes, hepatitis and kidney failure. The complete blood count and antioxidants were measured in these groups, and the results showed a significant decrease in hemoglobin and red blood cells count on the first and second days after the operation at all ages. In contrast, a significant increase in white blood cells count, MDA, NO level and GPX enzyme activity was observed in patients with cardiac disease associated with diabetes, hepatitis and renal failure at the first and second days after the operation compared to the control groups.

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