TY - JOUR ID - 260470 TI - Relationship between Serum IgE and Airway Responsiveness in Adults with Asthma JO - Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology JA - EAJBSC LA - en SN - 2090-0767 AU - Almehmadi, Mazen AU - Alghamdi, Saad AU - Kelantan, Mashael AU - Khan, Suleman AU - Alsugoor, Mahdi H. AU - Tasleem, Samiyah AU - Bantun, Farkad AU - Alsaiari, Ahad Amer AD - Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia AD - Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 21912, Saudi Arabia. AD - Department of Preventive Medicine & Public Health, Hera General Hospital, Makkah, Saudi Arabia AD - Department of Health and Biological Sciences Abasyn University Peshawar, Khyber Pakhtunkhwa-25130-Pakistan AD - Department of Emergency Medical Services, Faculty of Health Sciences, AlQunfudah, Umm Al-Qura University, Makkah 21912, Saudi Arabia. AD - Department of Microbiology, University of Karachi-75270-Pakistan. AD - Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah 21912, Saudi Arabia. AD - Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia. Y1 - 2022 PY - 2022 VL - 14 IS - 2 SP - 53 EP - 56 KW - Asthma KW - IgE KW - bronchi DO - 10.21608/eajbsc.2022.260470 N2 - Several cell types and a wide variety of inflammatory mediators are involved in the chronic airway inflammation that characterizes asthma. The study aims to uncover a link between high serum immunoglobulin E IgE levels and childhood asthma. This cross-sectional study was conducted from March to July 2022 at Khyber Teaching Hospital Peshawar, Pakistan. Asthma patients traveling to the clinic's out-of-the-way chest medication branch were given a clear explanation of the review's goal, its system, and its security measures. This study included 65 patients. This study lists demographic, clinical, and useful characteristics. The research review included 18–60-year-old patients. 40 (66.67%) of our 60 patients were men, and 20 (33.33%) were women. Out of 60 cases, 56.67% had severe asthma. The researchers concluded that the serum levels of immunoglobulin E in asthmatics were much higher than those in normal patients. The severity of the patient's asthma was correlated with an increase in their IgE levels, on average. UR - https://eajbsc.journals.ekb.eg/article_260470.html L1 - https://eajbsc.journals.ekb.eg/article_260470_ecc529d4724c35413bd64a69ee4de85f.pdf ER -