Investigation of Vaginal Microbiota in Infertile Women Compared with Fertile and Evaluation of Correlation Between Elafin As an antimicrobial Peptide with Some Hormones

Khalaf, Hanade M.; Nijris, Osama N.; Hatam, Aseel M.; Mahdi, Ali A.

doi:10.21608/eajbsc.2023.330425

Investigation of Vaginal Microbiota in Infertile Women Compared with Fertile and Evaluation of Correlation Between Elafin As an antimicrobial Peptide with Some Hormones

Document Type : Original Article

Authors

¹ Department of Pathological Analysis, College of Applied Sciences, Samarra University, IRAQ.

² Department of Medical Laboratories, College of Health and Medical Technologies,Middle Technical University, IRAQ.

10.21608/eajbsc.2023.330425

Abstract

Background: This study included the collection of 90 blood samples and 90 vaginal swabs, in order to isolate the microbial samples. Method: The samples were diagnosed based on routine methods.Result: The results of culture and pre-diagnosis showed that 86 swabs gave a positive result for bacterial and yeast growth on the media used. The results showed that Candida albicans was the most common pathogen among infertile women, Staphylococcus aureus and Escherichia coli. While in the control group, Lactobacillus was the most common, and then E.coli. Results showed a significant increase at the level (P≤0.05) in the concentrations existence of negative correlation between Elafin and (LH and FSH) and positive correlation between Elafin and (GNRH, β-Lipotropin and subfatin).

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