Estimation of The Levels of Hormonal Parameters in Patients with Osteoporosis and Heart Diseases in Samarra City

Majeed, Muhannad E.; Abd-al-Wahab, Wijdan I. A.; Marbut, Mousa M.

doi:10.21608/eajbsc.2023.330065

Estimation of The Levels of Hormonal Parameters in Patients with Osteoporosis and Heart Diseases in Samarra City

Document Type : Original Article

Authors

¹ Biology Department, college of Education ,University of Samarra.

² Biotechnologt Department. Al-Farabi University Collage

10.21608/eajbsc.2023.330065

Abstract

A Cross-Sectional study that includes an assessment of the relation of the physiological and immunological factors among postmenopausal women with osteoporosis and heart diseases who attended Samarra General Hospital in Salah AL-Din Governorate .The study started from January 2022 to November 2022 on a study population whose ages ranged from 45-70 years, their total number is 100 women, 25 of whom are healthy who are considered as a control group, and 75 of them are represented by groups of patients that were distributed into three main groups: 25 women with heart disease only include myocardial infarction and 25 women with osteoporosis only and 25 women with heart disease and osteoporosis .Blood samples were collected from patients and healthy subjects and then serum separated for testing. The present study was designed to obtain more clarification of some hormonal changes in women patients with osteoporosis and heart diseases. It find out the role of some hormonal parameters Calcitonin(CT), Parathyroid (PTH), and Estrogen ( E₂)   in the serum of women patients with osteoporosis and heart diseases. The result of hormonal parameters include: Calcitonin, Estrogen showed significantly decreased (P≤0.05) in groups of osteoporosis, Heart disease, and osteoporosis with heart disease in comparison with control group. Parathyroid showed a significant increase (P≤0.05) in groups of osteoporosis, heart disease, and osteoporosis with heart disease in comparison with the control group.
               To investigate the physiological relationship between hormonal parameters, calcitonin and estrogen and parathyroid in patients of osteoporosis and heart diseases in Samarra city.
               Serum calcitonin and estrogen showed significant decreases (P≤0.05) in groups of osteoporosis, heart disease, and osteoporosis with heart disease in comparison with the control group but Parathyroid showed a significant increase (P≤0.05) in groups of osteoporosis, heart disease, and osteoporosis with heart disease in comparison with control group.

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