Role of Integrons 1 and 2 in Proteus spp. and Evaluation of Some Antibiotic's Resistance Genes

Document Type : Original Article

Authors

Al-Furat Al-Awsat Technical University, College of Health and Medical Techniques, Kufa, Iraq

Abstract

A total number of 150,86 samples (57.3%) of samples were females, and 64 (42.7%) of samples were males, so from total specimens of 150 showed significant bacterial growth. The most common pathogen was proteus spp (50%), Staphylococcus spp (8.3%) Klebsiella pneumoniae (11.7 %), streptococcus spp (16.7%), Serratia marcescens (13,3%), Antibacterial susceptibility test was conducted for 30 proteus spp isolates against 20 commonly used antibacterial agents by using the disk diffusion method, the highest rate of resistance was seen with Ampicillin 30/30(100%) followed Amoxicillin- clavulanic Acid 29/30 (97.5%) and colistin 27/30 (90 %) and the low rate resistance was seen with Meropenem 0/30 (0%) and imipenem was 1/30 (7.5%), the results showed presence of integron-1 in Proteus spp isolates, from the 30 (100%) isolates of  Proteus spp was 5 (16.65 %) is positive and integron-2 was ( 83.25 %) 25 positive for 30 proteus spp isolates. The results showed that the (blaOXA-1) gene was detected in Proteus spp isolates, from the 30 (100%) isolates 9 (30.3 %) were positive. where have blaTEM gene, the result was (40%) positive, and bla SHV gene was found in 2 isolates (6.66%), and finally the bla AMP-c gene was positive in 6 isolates (19%).

Keywords

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Volume 15, Issue 2
December 2023
Pages 367-377

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